Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 324054-99-1
Chemical Name: N-[2-(Aminocarbonyl)phenyl][1,1′-biphenyl]-4-carboxamide; N-(2-carbamoylphenyl)-[1,1'-biphenyl]-4-carboxamide
Purity: >98% (HPLC)
Novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-L1 knock-in B16F10-bearing mouse model without the induction of observable liver toxicity
Ref: https://www.sciencedirect.com/science/article/pii/S1476558621000026
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