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CAS: N/A

 

Chemical Name: 1-(3-(2-Ethoxyethoxy)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-2-(trifluoromethyl)-1H-benzo[d]imidazole-5-carboxylic acid

 

 
GLXC-23437For Lab R&D Uses Only
        Cat No: GLXC-23437

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

The first "Gatekeeper" RXR antagonist that does not show allosteric inhibition in permissive RXR heterodimers, binding domain (LBD) at the entrance of the ligand binding pocket (LBP), blocking access to the LBP and thus serving as a "gatekeeper"

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01354

 

Analytical data click for PDF file

 

 

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