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CAS: 2382769-46-0
Chemical Name: (1R,2R,4S)-2-Methoxy-4-((R)-2-((3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-5,9,27-trihydroxy-10,21-ddimethoxy-6,8,12,14,20,26-hexamethyl-1,11,28,29-tetraoxo-1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-tetracosahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontin-3-yl)propyl)cyclohexyl (30-((4-(7-(6-Aminopyridin-3-yl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine-4-carbonyl)-2-fluoro-3-methylphenyl)sulfonyl)-27-oxo-3,6,9,12,15,18,21,24-octaoxa-28-azatriacontyl)carbamate
Purity: >98% (HPLC)
Novel bi-steric mTORC1 inhibitor, exhibiting potent and selective (>10-fold) inhibition of mTORC1 over mTORC2
Reference:
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.2c01658
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