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CAS: 1799711-22-0
Chemical Name: (1R)-3-(3,4-Dimethoxyphenyl)-1-(3-(4-((4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)amino)-4-oxobutanamido)phenyl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate
Purity: >98% (HPLC)
Proteolysis targeting chimeras (PROTAC), potently decreasing FKBP12 abundance in MV4;11 cells, leading to over 80% reduction of FKBP12 at 0.1 μM and 50% reduction at 0.01 μM
Ref: https://science.sciencemag.org/content/348/6241/1376.long
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