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13PCSK9i

 

CAS: N/A

 

Chemical Name: 3-((6S,9S,12S,15S,18S,21S,24S,27S,29aS,35S,38S,44R,46aS)-15,21-Bis([1,1'-biphenyl]-4-ylmethyl)-38-benzyl-44-(ethylcarbamoyl)-24,27-bis((R)-1-hydroxyethyl)-35-isopropyl-6,12,13,18,19-pentamethyl-5,8,11,14,17,20,23,26,29,34,37,40,46-tridecaoxotetratetracontahydro-5H-dipyrrolo[2,1-f:2',1'-g1][1]thia[4,7,10,13,16,19,22,25,28,31,34,37,40]tridecaazacyclodotetracontin-9-yl)propanoic acid

 

 
GLXC-25086For Lab R&D Uses Only
        Cat No: GLXC-25086

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel PCSK9-LDLR disruptor, reducing plasma cholesterol levels and increases hepatic LDLR density in a dose-dependent manner, functioning by a unique, allosteric mechanism and being the smallest molecule identified to date with in vivo PCSK9-LDLR disruptor function

 

Ref: https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(21)00401-3

 

Analytical data click for PDF file

 

 

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