Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 6-(tert-Butyl)-5-(3,4-dichlorophenyl)-4-(2-(trifluoromethoxy)phenoxy)thieno[2,3-d]pyrimidine
Purity: >98% (HPLC)
Novel positive allosteric modulator (PAM) of mas-related G protein-coupled receptor X1 (MRGPRX1), reducing behavioral heat hypersensitivity in humanized MRGPRX1 mice, demonstrating the therapeutic potential in treating neuropathic pain
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01709
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