Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2503015-75-4
Chemical Name: 1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl)-3-((6-(trifluoromethyl)pyridin-3-yl)methyl)urea
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel orally active and selective CSF1R inhibitor (IC50 = 0.53 nM), specifically inhibited protumor M2-like macrophage survival with a minimal effect on antitumor M1-like macrophage growth, exhibiting antitumor and immunomodulatory activity in a murine colon tumor model
https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01006
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