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Cyclorasin B4-27




Chemical Name: Benzene-1,3,5-tricarbonyl[2-Nal1,Lys6,Dap11] 2-Nal-Ser-Asn-D-2-Nal-Phg-Lys-D-Phe-Gln-Arg-Arg-Dap-Orn-D-Arg-Phe-D-Ala-NH2


GLXC-24408For Lab R&D Uses Only
        Cat No: GLXC-24408


Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)



Product Description:

Novel bicyclic peptidyl pan-Ras inhibitor, binding selectively to the GTP-bound forms of wild-type and mutant Ras isoforms (KD = 21 nM for KRasG12V-GppNHp) and being highly cell-permeable and metabolically stable (serum t1/2 > 24 h)




Analytical data click for PDF file



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