Glixx Laboratories Inc
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Chemical Name: (S)-2-((1-(3-(4-(tert-Butyl)cyclohexyl)-4-(pyrrolidin-3-yloxy)benzoyl)piperidin-4-yl)oxy)-4-(piperazin-1-yl)benzonitrile dihydrochloride
Purity: >98% (HPLC)
Novel β-catenin/B-cell lymphoma 9 (BCL9) inhibitor, disrupting the β-catenin/BCL9 protein-protein interaction (PPI) with a Ki of 0.96 μM and without affecting the β-catenin/E-cadherin interaction in living cells, displaying good selectivity for β-catenin/BCL9 over β-catenin/E-cadherin PPIs
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