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Glixx Laboratorie
CAS: N/A
Chemical Name: JC-TH-acetate-4; [(1S,2S,3R,4S,4aR,11bR)-2,3,4-trihydroxy-6-oxo-2,3,4,4a,5,11b-hexahydro-1H-[1,3]dioxolo[4,5-j]phenanthridin-1-yl]methyl acetate
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel apoptosis inducer, mitochondrially targeting chemoresistant osteosarcoma (OS) cells (Saos-2, U-2 OS), inducing collapse of mitochondrial membrane potential (MMP), increasing reactive oxygen species (ROS) production in isolated mitochondria, and causing release of apoptosis inducing factor (AIF) and endonuclease G (EndoG) from isolated mitochondria
Reference:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3244407/
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