Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: SP2012; LRRFSTMPFMF-Abu-NINNV-Abu-NF; Leu-Arg-Arg-Phe-Ser-Thr-Met-Pro-Phe-Met-Phe-Abu-Asn-Ile-Asn-Asn-Val-Abu-Asn-Phe
Purity: >98% (HPLC)
Novel integrin-binding peptide, inhibiting hepatocyte growth factor (HGF) signaling through Met-integrin interactions, also being an antiangiogenic agent by reducing phosphorylation of VEGR2, IGFR, and PDGFR, stabilizing vessels by disrupting α5β1 signaling and relocating Tie2 receptors to the junction
References:
1) https://www.nature.com/articles/s41540-019-0107-2
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731893/
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