Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 4-Isopropyl-6-((4-(isoquinolin-4-yl)pyrimidin-2-yl)amino)-1,3-dimethyl-3,4-dihydroquinoxalin-2(1H)-one
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent dual inhibitor of CDK9 and BET proteins with balanced activities of BRD4 (IC50 = 12.7 nM) and CDK9 (IC50 = 22.4 nM), as well as good antiproliferative activities on a small cancer cell panel
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00962
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