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Glixx Laboratorie
CAS: 1021920-32-0
Chemical Name: 1,3-Dihydro-1-[2-(tetrahydro-2H-pyran-4-yl)ethyl]-6-[4-(1H-1,2,4-triazol-5-yl)phenyl]-2H-imidazo[4,5-b]pyrazin-2-one
Purity: >98% (HPLC)
Novel dual mTORC1/mTORC2 inhibitor, inhibiting naïve T cell activation and the expression of T-cell activation markers, inducing specific tolerance against alloantigens, while preserving anti-cytomegalovirus response
References:
1) https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.13984
2) https://www.oncotarget.com/article/3378/text/
3) https://mct.aacrjournals.org/content/13/2/504.long
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