Glixx Laboratories Inc

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RB-3

 

CAS: N/A

 

Chemical Name: 3-(5-Chloro-1H-indol-4-yl)-5-(1H-indol-4-yl)-4-propan-2-yl-1H-pyrrole-2-carboxylic acid

 

 
GLXC-24403For Lab R&D Uses Only
        Cat No: GLXC-24403

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel inhibitor of polycomb repressive complex 1 (PRC1), directly binding to RING1B-BMI1, the heterodimeric complex constituting the E3 ligase activity of PRC1, blocking the association of RING1B-BMI1 with chromatin and inhibiting H2A ubiquitination, leading to a reduction in H2Aub and differentiation in TEX cells

 

Ref: https://www.nature.com/articles/s41589-021-00815-5

 

Analytical data click for PDF file

 

 

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