Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Chemical Name: 3-(5-Chloro-1H-indol-4-yl)-5-(1H-indol-4-yl)-4-propan-2-yl-1H-pyrrole-2-carboxylic acid
Purity: >98% (HPLC)
Novel inhibitor of polycomb repressive complex 1 (PRC1), directly binding to RING1B-BMI1, the heterodimeric complex constituting the E3 ligase activity of PRC1, blocking the association of RING1B-BMI1 with chromatin and inhibiting H2A ubiquitination, leading to a reduction in H2Aub and differentiation in TEX cells
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