Glixx Laboratories Inc

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LD4172

 

CAS: N/A

 

Chemical Name: N1-(3-(4-Amino-3-(1-(2-(3-(trifluoromethoxy)phenyl)acetyl)indolin-5-yl)-1H-indol-1-yl)propyl)-N12-((S)-1-((2R,4S)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)dodecanediamide

 

 
GLXC-27139For Lab R&D Uses Only
        Cat No: GLXC-27139

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

First-in-class highly potent and specific RIPK1 degrader, potently inducing RIPK1 degradation with high specificity and substantially sensitizes multiple preclinical cancer models to anti-PD1 therapy

 

Reference:

https://www.biorxiv.org/content/10.1101/2024.03.25.586133v1.full

 

Analytical data click for PDF file

 

 

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