Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: Sodium (2R,3S,4R,5R,6S)-5-dodecanamido-4,6-bis(dodecanoyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl phosphate
Purity: >98% (HPLC)
Novel TLR4 Agonist as a Vaccine Adjuvant, binding inside the MD-2 pocket, showing a different mechanism of action and immunofluorescence microscopy showed no NF-κB nor p-IRF-3 nuclear translocation but rather MAPK and NLRP3-dependent inflammasome activation
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01998
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