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CAS: N/A
Chemical Name: N-(3-((((1S,2R)-2-((E)-2-Cyano-4,4-dimethylpent-2-enamido)cyclopentyl)oxy)methyl)benzyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel reversible covalent inhibitor of the cyclin-dependent kinase 5 (Cdk5)-mediated phosphorylation of PPARγ at Ser245, a key factor in the insulin-sensitizing effect of PPARγ-targeted drugs
References:
https://www.nature.com/articles/s41598-019-47672-w
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00048
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