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CAS: N/A
Chemical Name: (S)-1-(Acetylglycyl)-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide
Purity: >98% (HPLC)
Novel dual inhibitor of the iP subunit LMP2 and the constitutive proteasome (cP) catalytic subunit Y, ameliorating cognitive impairments in mouse models of Alzheimer’s disease (AD) independently of amyloid deposits
References:
1) https://www.nature.com/articles/s41598-019-54846-z
2) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010139
3) https://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-7-187
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