Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Chemical Name: 4-OI; 2-Methylidene-4-octoxy-4-oxobutanoic acid
Purity: >98% (HPLC)
Selective inhibitor of NLRP3 inflammasome activation, inhibiting the interaction between NLRP3 and NEK7, a key step in the activation process, and "dicarboxypropylated" C548 on NLRP3, also inhibiting NLRP3-dependent IL-1β release from PBMCs isolated from cryopyrin-associated periodic syndrome (CAPS) patients, and reduced inflammation in an in vivo model of urate-induced peritonitis
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