Glixx Laboratories Inc

               Your exclusive source for bioactive molecules

Glixx Laboratorie

 

   sales@glixxlabs.com      Toll-Free: (855)Go-Glixx   Tel: 781-333-5348    Fax: 781-333-5368 
4-Octyl Itaconate

 

CAS: 3133-16-2

 

Chemical Name: 4-OI; 2-Methylidene-4-octoxy-4-oxobutanoic acid

 

 
GLXC-22752For Lab R&D Uses Only
        Cat No: GLXC-22752

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Selective inhibitor of NLRP3 inflammasome activation, inhibiting the interaction between NLRP3 and NEK7, a key step in the activation process, and "dicarboxypropylated" C548 on NLRP3, also inhibiting NLRP3-dependent IL-1β release from PBMCs isolated from cryopyrin-associated periodic syndrome (CAPS) patients, and reduced inflammation in an in vivo model of urate-induced peritonitis

 

References:

1) https://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30411-3

2) https://www.nature.com/articles/s42255-020-0210-0

3) https://elifesciences.org/articles/54877

 

Analytical data click for PDF file

 

 

Place an order!

Price & Availability





POA
 








Bulk inquiry contact:
sales@glixxlabs.com
service@glixxlabs.com