Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1570496-34-2
Chemical Name: 5-(5-Methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole
Purity: >98% (HPLC)
Novel potent inhibitor of complex I of the mitochondrial electron transport chain, robustly inhibiting proliferation and inducing apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS
References:
1) https://www.mdpi.com/2072-6694/12/9/2400
2) https://www.frontiersin.org/articles/10.3389/fonc.2020.00991/full
3) https://jitc.bmj.com/content/8/1/e000289.long
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