Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 20562-03-2
Chemical Name: α-Chaconine; (2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[[(1S,2S,7S,10R,11S, 14S,15R,16S,17R,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-yl]oxy]-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol
For Lab R&D Uses Only
Purity: >98% (HPLC)
Natural inhibitor of RL95-2 endometrium cancer cell proliferation by reducing expression of Akt (Ser473) and ERα (Ser167), inducing pro-inflammatory mediators via AP-1 inactivation in RAW 264.7 macrophages and protecting mice from endotoxin shock
References:
1) https://www.jstage.jst.go.jp/article/bpb/33/4/33_4_622/_article
2) https://pubs.acs.org/doi/10.1021/jf072423r
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