Glixx Laboratories Inc

               Your exclusive source for bioactive molecules

Glixx Laboratorie

 

   sales@glixxlabs.com      Toll-Free: (855)Go-Glixx   Tel: 781-333-5348    Fax: 781-333-5368 
MLKL PROTAC 36

 

CAS: N/A

 

Chemical Name: MLKL degrader 36; 3-(4-((Difluoromethyl)sulfonamido)phenyl)-5-((3-((8-(9-(3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-methoxybenzoyl)-3,9-diazaspiro[5.5]undecan-3-yl)-8-oxooctyl)oxy)phenyl)amino)-1H-pyrazole-4-carboxamide

 

 
For Lab R&D Uses Only
        Cat No: GLXC-27657

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent MLKL PROTAC, effectively degrading MLKL (Dmax >90%) and completely abrogating cell death in a TSZ model of necroptosis (Emax TSZ 100%), protecting cells from necroptosis

 

Reference:

https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.3c00665

 

Analytical data click for PDF file

 

 

Place an order!

Price & Availability





POA
 








Bulk inquiry contact:
sales@glixxlabs.com
service@glixxlabs.com