Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 845811-30-5
Chemical Name: TZL; (1R,2S,3R,6S,10S,12R,14R,15R,Z)-1,2-dihydroxy-3,7,7,10,14-pentamethyl-11-oxo-16,17-dioxatricyclo[10.3.1.13,6]heptadec-8-en-15-yl (E)-3-methylpent-2-enoate
For Lab R&D Uses Only
Purity: >98% (HPLC)
Natural agonist of TPRC1/4/5 channels, also acting as a dual PKCα and PKCθ activator, inducing an insulin resistant phenotype by inhibiting IRS1 and the PI3K/Akt pathway, activating the heat shock factor 1 (HSF1) transcription factor driving glucose dependency
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Tonantzitlolone&sort=date
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