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Glixx Laboratorie
CAS: 1959551-26-8
Chemical Name: (S)-5-((1-(4,4-Difluoro-3-(3-fluoro-1H-pyrazol-1-yl)butanoyl)-4-hydroxypiperidin-4-yl)methyl)-1-(4-fluorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
Cat No: GLXC-10966
For Lab R&D Uses Only
Purity: >98% (HPLC)
Storage: Refrigerator (4 °C)
Novel potent and selective inhibitor of ubiquitin-specific protease 7 (USP7), destabilizing USP7 substrates including MDM2, increasing levels of p53, and resulting in the transcription of p53 target genes, inducing the tumour suppressor p21, and inhibiting tumour growth
References:
1) https://www.nature.com/articles/s41422-018-0091-x
2) https://www.nature.com/articles/nature24451
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