Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1332175-56-0
Chemical Name: 6-[3-(4-Fluorobenzyl)-3-(hydroxymethyl)piperidin-1-yl]pyrazine-2-carboxamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel TDP-43 ligand, binding to TDP-43's RRM1 and RRM2 domains, partially disrupting TDP-43's interaction with the hexanucleotide RNA repeat of the disease-linked c9orf72 gene, improving larval turning, an assay measuring neuromuscular coordination and strength
Ref: https://pubs.acs.org/doi/10.1021/acschembio.9b00481
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