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CAS: N/A
Chemical Name: (2S,4R)-1-((S)-2-(4-(4-(5-((Furan-2-ylmethyl)amino)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)benzamido)butanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: >98% (HPLC)
Novel EED-targeted bivalent chemical degrader, selectively degrading EED, EZH2, and SUZ12 via recruitment of VHL, resulting in loss of PRC2 catalytic activity and decreased H3K27me3 levels
Ref: https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(19)30364-2
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