Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1227962-62-0
Chemical Name: Marinopyrrole-A; [4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(2-hydroxyphenyl)methanone
Cat No: GLXC-05690
For Lab R&D Uses Only
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Selective Mcl-1 antagonist that overcomes ABT-737 resistance, blocking the binding of Bim BH3 α-helix to Mcl-1 but not Bcl-XL
References:
1) https://www.sciencedirect.com/science/article/abs/pii/S0006291X20304733?
2) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217657
3) https://www.tandfonline.com/doi/abs/10.1080/07391102.2018.1508371?journalCode=tbsd20
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