Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1809010-50-1
Chemical Name: BCX7353; 2-[3-(Aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Purity: >98% (HPLC)
Novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE
References:
1) https://onlinelibrary.wiley.com/doi/10.1111/all.14670
2) https://www.jacionline.org/article/S0091-6749(20)31484-6/fulltext
3) https://www.futuremedicine.com/doi/10.2217/imt-2019-0128
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