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Glixx Laboratorie
CAS: 2131184-57-9
Chemical Name: VU0661013; VU-013; (R)-3-(7-Chloro-10-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-4-methyl-1-oxo-6-(1,3,5-trimethyl-1H-pyrazol-4-yl)-3,4-dihydropyrazino[1,2-a]indol-2(1H)-yl)-1-methyl-1H-indole-5-carboxylic acid
Purity: >98% (HPLC)
Novel highly potent and specific inhibitor of myeloid cell leukemia-1 (Mcl-1), binding to Mcl-1 with picomolar affinity and inhibiting growth of Mcl-1-dependent tumor cell lines in the nanomolar range
References
1) https://www.oncotarget.com/article/27070/text/
2) https://cancerdiscovery.aacrjournals.org/content/8/12/1566.long
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