Glixx Laboratories Inc
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Chemical Name: (S)-N-(4-(((1H-Benzo[d]imidazol-2-yl)methyl)(5,6,7,8-tetrahydroquinolin-8-yl)amino)butyl)nicotinamide
Purity: >98% (HPLC)
The niacin derivative of AMD070 as potent CXCR4 antagonist, demonstrating stronger pro-apoptotic effects than AMD070 in vitro, inducing expression of pro-apoptotic genes of the BCL2-family in CXCR4-positive lymphoma cell lines, resulting in the reduced expression of JNK-, ERK1/2- and NF-κB/BCR-target genes
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