Glixx Laboratories Inc

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Glixx Laboratorie

 

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PROTAC B3

 

CAS: N/A

 

Chemical Name: (2S,4R)-1-((S)-3,3-Dimethyl-2-(9-(4-((4-(3-(pyridin-3-ylmethyl)ureido)phenyl)sulfonyl)piperazin-1-yl)nonanamido)butanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide

 

 
GLXC-26677For Lab R&D Uses Only
        Cat No: GLXC-26677

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly potent nicotinamide phosphoribosyltransferase (NAMPT) degrader for efficient treatment of ovarian cancer, displayed excellent degradation activity (DC50 < 0.17 nM, Dmax > 90%) and antiproliferative potency against A2780 cells (IC50 = 1.5 nM)

 

Reference:

https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.2c01990

 

Analytical data click for PDF file

 

 

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