Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2406205-61-4
Chemical Name: N-((1S,2R)-1-(4-Fluoro-3-methylphenyl)-1-hydroxybutan-2-yl)-2-oxoindoline-4-carboxamide
Purity: >98% (HPLC)
Novel stabilizer of Zα1-antitrypsin, blocking Zα1-antitrypsin polymerisation in vitro, reducing intracellular polymerisation and increasing the secretion of Zα1-antitrypsin threefold in an iPSC model of disease
References:
1) https://www.embopress.org/doi/full/10.15252/emmm.202013167
2) https://www.nature.com/articles/s41467-020-20147-7
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