Glixx Laboratories Inc
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Chemical Name: (12S,4S)-N-((S)-1-((R)-2-Methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)-2,15-dioxo-7-oxa-3-aza-1(2,1)-pyrrolidina-6(1,4)-benzenacyclopentadecaphane-4-carboxamide
Purity: >98% (HPLC)
Novel macrocyclic immunoproteasome inhibitor, effectively inhibiting the catalytic activity of immunoproteasome (iP) in ABCB1-overexpressing cells (IC50: 105 nM) and having metabolic stability superior to its linear counterpart
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