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CAS: N/A
Chemical Name: 4-((4-(1-(3-(Cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-N-(3-(4-(4-(2,6-dioxopiperidin-3-yl)phenyl)piperazin-1-yl)propyl)benzamide
Purity: >98% (HPLC)
Novel Potent and Selective Janus Kinase 2/3 Directing PG-PROTAC, displaying high selectivity over GSPT1 and other members of the JAK family and potency in patient-derived ALL cells containing both JAK2 fusions and CRLF2 rearrangements
Ref: https://pubs.acs.org/doi/10.1021/acsmedchemlett.1c00650
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