Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2139288-26-7
Chemical Name: N-((R)-3-(4-(2-(3,5-Dichloro-4-((S)-3-chloro-2-hydroxypropoxy)phenyl)propan-2-yl)phenoxy)-2-hydroxypropyl)methanesulfonamide
Purity: >98% (HPLC)
Potent androgen receptor N-terminal domain antagonist, decreasing expression of DNA repair genes, sensitizing prostate cancer cells that express full-length AR and AR-Vs to radiotherapy
References:
1) https://febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.12770
2) https://www.mdpi.com/2072-6694/12/7/1991
3) https://ascopubs.org/doi/abs/10.1200/JCO.2019.37.7_suppl.220
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