Glixx Laboratories Inc

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ARD-69

 

CAS: N/A

 

Chemical Name: (2S,4R)-N-((S)-3-(4-((4-(((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethyl-cyclobutyl)carbamoyl)phenyl)ethynyl)-[1,4′-bipiperidin]-1′-yl)-1-(4-(4-methylthiazol-5-yl)phenyl)-3-oxopropyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide

 

 
GLXC-11080For Lab R&D Uses Only
        Cat No: GLXC-11080

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly potent proteolysis targeting chimera (PROTAC) degrader of androgen receptor (AR), being capable of reducing the AR protein level by >95% in prostate cancer cell lines and effectively suppressing AR-regulated gene expression

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.8b01631

 

Analytical data click for PDF file

 

 

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