Glixx Laboratories Inc
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Chemical Name: (2S,4R)-N-((S)-3-(4-((4-(((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethyl-cyclobutyl)carbamoyl)phenyl)ethynyl)-[1,4′-bipiperidin]-1′-yl)-1-(4-(4-methylthiazol-5-yl)phenyl)-3-oxopropyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide
Purity: >98% (HPLC)
Novel highly potent proteolysis targeting chimera (PROTAC) degrader of androgen receptor (AR), being capable of reducing the AR protein level by >95% in prostate cancer cell lines and effectively suppressing AR-regulated gene expression
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