Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Chemical Name: 5-(2,4-Difluoro-3-((3-((4-fluorophenyl)carbamoyl)-1H-pyrazol-4-yl)carbamoyl)phenyl)picolinamide
Purity: >98% (HPLC)
Novel potent CDK2 inhibitor with selectivities above 10-fold over CDK1/4/6/7/9/12 above 10-fold, displaying anti-proliferative activity against A2058 melanoma and MV4-11 leukemia cell lines and low toxicity on human normal cell lines, inhibiting CDK2-medieated phosphorylation of Rb, blocking cell cycle progression, and inducing apoptosis
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