Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 867017-68-3
Chemical Name: TC-S 7001; Azaindole-1; 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
Cat No: GLXC-06898
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Highly potent and selective ROCK1 and ROCK2 inhibitor [ROCK1 (h) (IC50 = 0.6 nM), ROCK2 (h) (IC50 = 1.1 nM), ROCK2 (m) (IC50 = 2.4 nM), ROCK2 (r) (IC50 = 0.8 nM)]
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564057/
2) https://cdnsciencepub.com/doi/10.1139/y2012-061
3) https://erj.ersjournals.com/content/36/4/808.long
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