Glixx Laboratories Inc
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Chemical Name: (R)-N-(2-((5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)amino)-3-fluoro-5-(4-morpholinopiperidin-1-yl)phenyl)acrylamide
Purity: >98% (HPLC)
Novel highly selective covalent inhibitor of wild-type and gatekeeper mutant FGFR4, exhibiting excellent potency against FGFR4, FGFR4V550L, and FGFR4V550M with nanomolar activity in both the biochemical and cellular assays while sparing FGFR1/2/3
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