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Glixx Laboratorie
CAS: 2750570-55-7
Chemical Name: (S)-4-(3-(4-(4-Acryloylpiperazin-1-yl)-6-((S)-2,4-dimethylpiperazin-1-yl)pyridin-2-yl)-1,2,4-oxadiazol-5-yl)-2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile
Purity: >98% (HPLC)
Novel potent, in vivo active KRASG12C inhibitor, demonstrating around 500-fold improvement in both the second-order rate constant and the GDP-KRAS::SOS1 protein-protein interaction assay
Reference:
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.2c01120
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