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Glixx Laboratorie
CAS: N/A
Chemical Name: 6,7-Dichloro-2,3,5,8-tetrahydroxynaphthalene-1,4-dione
Purity: >98% (HPLC)
Novel inhibitor of protein-protein interaction (PPI), targeting integrin αvβ3-osteopontin interface, blocking OC maturation from murine bone marrow-derived macrophages, as well as the resorptive function of OCs, impairing downstream signaling of integrin αvβ3 linked to Pyk2, c-Src, PLCγ2, and Vav3
Ref: https://www.sciencedirect.com/science/article/pii/S0142961216301685?via%3Dihub
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