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Glixx Laboratorie
CAS: N/A
Chemical Name: (Z)-2-(2-((3-Oxobenzo[4,5]imidazo[2,1-b]thiazol-2(3H)-ylidene)methyl)-1H-indol-1-yl)acetic acid
Purity: >98% (HPLC)
Novel blocker of TG2-FN interaction, inhibiting binding of a TG2 peptide to a 42-kDa fragment of fibronectin in a dose-dependent manner, reducing TG2 stabilization, mimicking the effects of GTP, a known negative allosteric regulator of TG2 enzymatic function, showing little cell toxicity
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