Glixx Laboratories Inc

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UC-514321

 

CAS: 299420-83-0

 

Chemical Name: 6-((3,5-di-tert-Butyl-4-methoxyphenyl)(morpholino)methyl)benzo[d][1,3]dioxol-5-ol

 

 
GLXC-21598For Lab R&D Uses Only
        Cat No: GLXC-21598

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel selective TET1-signaling inhibitor, directly bind to the DBD of STAT3/5, showing an enhanced effect in repressing the viability of TET1-high AML (including MONOMAC-6, THP-1, and KASUMI-1) cells, as compared with NSC-370284 and other JAK/STAT inhibitors, e.g. Pacritinib, KW-2449, STAT3/5 inhibitor Stattic, or STAT5 inhibitor SC-355979

 

Ref: https://www.nature.com/articles/s41467-017-02290-w

 

Analytical data click for PDF file

 

 

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