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CAS: N/A
Chemical Name: N-(4-((1S,3R,5R)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide
Purity: >98% (HPLC)
Less active enantiomer of LGH447 (GLXC-10644), acting as a selective weak pan-PIM inhibitor (IC50 (µM): PIM1 0.095; PIM2 0.522; PIM3 0.369) in comparision with LGH447 (IC50 (µM): PIM1 0.001; PIM2 0.002; PIM3 0.002)
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.5b01275
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