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TRK Inhibitor 10g


CAS: 2937544-01-7


Chemical Name: TRK-IN-10g; 46-methyl-N-(5-cyclopropyl-3-(4-methylpiperazin-1-yl)methylphenyl)-14-oxo-5-oxa-13-aza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-45-carboxamide


GLXC-27727For Lab R&D Uses Only
        Cat No: GLXC-27727


Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)



Product Description:

Novel potent and selective pan-anticancer type II TRK inhibitor, exhibiting excellent potency against wide type TRKA/C, TRKAG595R, TRKAG667C, and TRKAF589L with IC50 values of 5.21, 4.51, 6.77, 1.42, and 6.13 nM, respectively, demonstrating ideal antitumor efficacy in both BaF3-CD74-NTRK1G595R and BaF3-CD74-NTRK1G667C xenograft models



Analytical data click for PDF file



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