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Guggulsterone-52

 

CAS: N/A

 

Chemical Name: GG-52, (8R,9S,10R,13S,14S)-17(E/Z)-butylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-3H-cyclopenta[a]phenanthrene-3,16(2H)-dione

 

 
GLXC-22151For Lab R&D Uses Only
        Cat No: GLXC-22151

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel inhibitor of the activation of nuclear factor (NF)-κB signaling in bone marrow-derived dendritic cells,  significantly inhibiting LPS-induced IL-12p40 and TNF-α gene expression, IκBα degradation, and NF-κB DNA binding activity in BMDCs, attenuating colitis in IL-10 knockout mice

 

Ref: https://www.sciencedirect.com/science/article/abs/pii/S002432051300218X?via%3Dihub

 

 

Analytical data click for PDF file

 

 

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