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CAS: N/A
Chemical Name: N-(2-Chloro-6-methylphenyl)-2-((6-(4-(4-(4-(4-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)phenyl)piperazin-1-yl)-4-oxobutyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide
Purity: >98% (HPLC)
Novel phenyl dihydrouracil (PD)-based LCK-directing PD-PROTAC, displaying improved chemical stability and, consequently, improved protein degradation efficacy and cellular potency
Reference:
https://pubs.acs.org/doi/10.1021/acsmedchemlett.2c00436
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