Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 881001-19-0
Chemical Name: EGFR/ErbB-2/ErbB-4 Inhibitor; TKI39; N-(4-((3-Chloro-4-fluorophenyl)amino)pyrido[3,4-d]pyrimidin-6-yl)but-2-ynamide
Purity: >98% (HPLC)
Potent inhibitor of the ErbB receptor family (IC50 values are 0.3, 0.5 and 1.1 nM for ErbB1 (EGFR), ErbB4 and ErbB2 respectively)
References:
1) https://www.cell.com/cell-reports/fulltext/S2211-1247(15)01536-3
2) https://www.nature.com/articles/nbt.2017
3) https://pubs.acs.org/doi/10.1021/jm050936o
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