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Glixx Laboratorie
CAS: 1603845-32-4
Chemical Name: TX-85-1; N-(5-(1-(4-(4-Acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-phenoxyphenyl)acrylamide
Cat No: GLXC-05772
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
The first selective Her3 ligand, forming a covalent bond with Cys721 located in the ATP-binding site of Her3
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633287/
https://www.nature.com/articles/nchembio.1658
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