Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 181769-57-3
Chemical Name: Z-L-Nva-CONH-CH2-2-Py; Benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
Purity: >98% (HPLC)
Selective inhibitor of calpain I (mu-calpain, Ki = 19 nM); calpain II (m-calpain, Ki = 120 nM); and cathepsin B (Ki = 750 nM), being also active against human cathepsin L, a host-protease that is important for viral entry
References:
1) https://advances.sciencemag.org/content/early/2020/11/05/sciadv.abe0751
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605558/
3) https://www.sciencedirect.com/science/article/pii/S0166354220303387
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