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Calpain Inhibitor XII

 

CAS: 181769-57-3

 

Chemical Name: Z-L-Nva-CONH-CH2-2-Py; Benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate

 

 
GLXC-23176For Lab R&D Uses Only
        Cat No: GLXC-23176

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Selective inhibitor of calpain I (mu-calpain, Ki = 19 nM); calpain II (m-calpain, Ki = 120 nM); and cathepsin B (Ki = 750 nM), being also active against human cathepsin L, a host-protease that is important for viral entry

 

References:

1) https://advances.sciencemag.org/content/early/2020/11/05/sciadv.abe0751

2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605558/

3) https://www.sciencedirect.com/science/article/pii/S0166354220303387

 

Analytical data click for PDF file

 

 

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